Constrained thermoresponsive polymers – new insights into fundamentals and applications

• Patricia Flemming,
• Alexander S. Münch,
• Andreas Fery and
• Petra Uhlmann

Beilstein J. Org. Chem. 2021, 17, 2123–2163, doi:10.3762/bjoc.17.138

• the last decades, numerous stimuli-responsive polymers have been developed and investigated regarding their switching properties. In particular, thermoresponsive polymers, which form a miscibility gap with the ambient solvent with a lower or upper critical demixing point depending on the temperature

• of solvents. In solution, stimuli responsive polymers undergo a conformational, so-called coil-to-globule, transition. Depending on whether the solubility increases below (LCST for lower critical solution temperature [46][47][48][49]) or above (UCST for upper critical solution temperature [50][51][52

A switchable [2]rotaxane with two active alkenyl groups

• Xiu-Li Zheng,
• Rong-Rong Tao,
• Rui-Rui Gu,
• Wen-Zhi Wang and
• Da-Hui Qu

Beilstein J. Org. Chem. 2018, 14, 2074–2081, doi:10.3762/bjoc.14.181

• functional groups, such kind of MIMs has been used to construct stimuli-responsive materials, which diversified and improved the functions of traditional polymers. Up to now, the repertoire of available functional rotaxanes as building blocks for the fabrication of stimuli-responsive polymers remains limited

• . The naked alkenyl groups could react with other functional groups such as alkenyl and thiol groups to prepare stimuli-responsive polymers. Besides, the introduction of long alkyl chains makes the polymers easier to form gels. This kind of functional rotaxane enriches the species of building blocks to

• construct stimuli-responsive polymers and smart materials. Experimental General and materials 1H NMR and 13C NMR spectra were measured on a Bruker AV-400 spectrometer. The electronic spray ionization (ESI) mass spectra were tested on a LCT Premier XE mass spectrometer. Chemicals were used as received from

Stimuli-responsive HBPS-g-PDMAEMA and its application as nanocarrier in loading hydrophobic molecules

• Yongsheng Chen,
• Li Wang,
• Haojie Yu,
• Zain-Ul-Abdin,
• Ruoli Sun,
• Guanghui Jing,
• Rongbai Tong and
• Zheng Deng

Beilstein J. Org. Chem. 2016, 12, 939–949, doi:10.3762/bjoc.12.92

• -responsive nanocarriers; Introduction Stimuli-responsive polymers have attracted much attention due to their broad applications including drug controlled release [1][2][3][4][5], sensing [6][7] and 4D printing [8][9]. Nanocarriers prepared from amphiphilic stimuli-responsive polymers are promising

• that responds to changes in temperature, pH and ionic strength [13][14]. Among temperature-responsive polymers, PDMAEMA is an important material, as its low critical solution temperature (LCST) is close to the human body temperature. The stimuli-responsive polymers can be prepared by grafting or

• distribution which means that these stimuli-responsive polymers may be suitable for medicinal use. The encapsulation of hydrophobic molecules in HBPS-g-PDMAEMA aggregates To confirm the loading capability of HBPS-g-PDMAEMA aggregates for hydrophobic molecules, pyrene was used as a model molecule. Pyrene, a

Host–guest-driven color change in water: influence of cyclodextrin on the structure of a copper complex of poly((4-hydroxy-3-(pyridin-3-yldiazenyl)phenethyl)methacrylamide-co-dimethylacrylamide)

• Nils Retzmann,
• Gero Maatz and
• Helmut Ritter

Beilstein J. Org. Chem. 2014, 10, 2480–2483, doi:10.3762/bjoc.10.259

• experiments. Keywords: cyclodextrin; copolymer; copper(II) sulfate; supramolecular; water complex; Introduction In recent years, the interest in stimuli-responsive polymers increased exponentially [1]. Many polymers have been described, showing sensitivity towards e.g. light, pH and heat [2][3][4

Chiral recognition of macromolecules with cyclodextrins: pH- and thermosensitive copolymers from N-isopropylacrylamide and N-acryloyl-D/L-phenylalanine and their inclusion complexes with cyclodextrins

• Sabrina Gingter,
• Ella Bezdushna and
• Helmut Ritter

Beilstein J. Org. Chem. 2011, 7, 204–209, doi:10.3762/bjoc.7.27

• soluble stimuli-responsive polymers bearing phenylalanine moieties via host-guest interaction with β-cyclodextrin and randomly-methylated-β-cyclodextrin (RAMEB-CD). We synthesised N-acryloyl-D/L-phenylalanine monomers (2D, 2L) which were then copolymerised under free radical conditions with N

• of the side groups of copolymers 3D and 3L and their solubility behaviour were investigated by dynamic light scattering and 2D NMR spectroscopy, respectively. Keywords: amino acid; chiral recognition; cyclodextrins; LCST; stimuli-responsive polymers; Introduction Chiral recognition has attracted

Novel multi-responsive P2VP-block-PNIPAAm block copolymers via nitroxide-mediated radical polymerization

• Cathrin Corten,
• Katja Kretschmer and
• Dirk Kuckling

Beilstein J. Org. Chem. 2010, 6, 756–765, doi:10.3762/bjoc.6.89

• delivery systems. Keywords: block copolymers; N-isopropylacrylamide; nitroxide-mediated radical polymerization; stimuli-responsive polymers; 2-vinylpyridine; Introduction Functional polymers have attracted much attention because of their technological and scientific importance. Polymers, which respond